Slitrk6 Antibody | MyBioSource MBS150887 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Slitrk6 Antibody

catalog :

MBS150887

quantity :

0.1 mg

price :

375 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

Immunohistochemistry of Slitrk6 in human brain tissue with Slitrk6 antibody at 2.5 g/mL.

image 2 :

Immunofluorescence of Slitrk6 in Human Brain cells with Slitrk6 antibody at 20 g/mL.

product information

catalog number :

MBS150887

products type :

Antibody

products full name :

Slitrk6 Antibody

products short name :

[Slitrk6]

products name syn :

[Slitrk6; DFNMYP; SLIT and NTRK-like protein 6; SLIT and NTRK-like family, member 6]

other names :

[SLIT and NTRK-like protein 6; SLIT and NTRK-like protein 6; SLIT and NTRK-like protein 6; 4832410J21Rik; slit and trk like gene 6; SLIT and NTRK-like family, member 6]

products gene name :

[SLITRK6]

other gene names :

[SLITRK6; SLITRK6; DFNMYP]

uniprot entry name :

SLIK6_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

841

specificity :

This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

purity :

Slitrk6 Antibody is affinity chromatography purified via peptide column.

form :

Liquid

concentration :

1 mg/mL

storage stability :

Slitrk6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF). Optimal dilutions for each applications to be determined by the researcher.

app notes :

Slitrk6 antibody can be used for detection of Slitrk6 by Western blot at 0.5 - 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunofluorescence (IF)

other info1 :

Conjugate: Unconjugated. Immunogen: Slitrk6 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Slitrk6. Buffer: Slitrk6 Antibody is supplied in PBS containing 0.02% sodium azide.

other info2 :

Positive Control: MBS151737- SK-N-SH Cell Lysate. MBS154323-Human Brain Tissue Slide.

products description :

Slitrk6 Antibody: SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.

ncbi gi num :

59803110

ncbi acc num :

Q9H5Y7.3

uniprot acc num :

Q9H5Y7

ncbi summary :

This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014]

uniprot summary :

SLITRK6: Suppresses neurite outgrowth. Belongs to the SLITRK family. Protein type: Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 13q31.1. Cellular Component: cell surface; integral to plasma membrane. Biological Process: lens development in camera-type eye; vestibulocochlear nerve development; sensory perception of sound; synaptogenesis; startle response; axonogenesis; visual perception; adult locomotory behavior; multicellular organism growth; auditory receptor cell morphogenesis; auditory behavior; linear vestibuloocular reflex. Disease: Deafness And Myopia

size1 :

0.1 mg

price1 :

375 USD

more info or order :

MyBioSource product webpage