catalog number :
MBS150737
products full name :
LRRTM1 Antibody
products short name :
LRRTM1
products name syn :
LRRTM1; Leucine-rich repeat transmembrane neuronal protein 1; leucine rich repeat transmembrane neuronal 1
other names :
leucine-rich repeat transmembrane neuronal protein 1; Leucine-rich repeat transmembrane neuronal protein 1; leucine-rich repeat transmembrane neuronal protein 1; leucine-rich repeat transmembrane neuronal 1 protein; leucine rich repeat transmembrane neuronal 1
products gene name :
LRRTM1
other gene names :
LRRTM1; LRRTM1
uniprot entry name :
LRRT1_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
LRRTM1 antibody is predicted to not cross-react with other LRRTM family members.
purity :
LRRTM1 Antibody is affinity chromatography purified via peptide column.
storage stability :
LRRTM1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
LRRTM1 antibody can be used for detection of LRRTM1 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: LRRTM1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRTM1. Buffer: LRRTM1 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
LRRTM1 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.
ncbi gb acc num :
NM_178839.4
ncbi mol weight :
58,641 Da
uniprot summary :
LRRTM1: May play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons. Belongs to the LRRTM family. Protein type: Membrane protein, integral; Endoplasmic reticulum; Cell development/differentiation. Chromosomal Location of Human Ortholog: 2p12. Cellular Component: postsynaptic membrane; cell surface; growth cone; axon; endoplasmic reticulum; integral to membrane; excitatory synapse; cell junction. Biological Process: synapse organization and biogenesis; locomotory behavior; negative regulation of receptor internalization