product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
LRRFIP2 Antibody
catalog :
MBS150675
quantity :
0.1 mg
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
image
image 1 :
Western blot analysis of LRRFIP2 in rat colon tissue lysate with LRRFIP2 antibody at (A) 0.5 and (B) 1 g/mL.
image 2 :
Immunohistochemistry of LRRFIP2 in human colon tissue with LRRFIP2 antibody at 5 g/mL.
image 3 :
Immunofluorescence of LRRFIP2 in human colon tissue with LRRFIP2 antibody at 20 g/mL.
product information
catalog number :
MBS150675
products type :
Antibody
products full name :
LRRFIP2 Antibody
products short name :
[LRRFIP2]
products name syn :
[LRRFIP2; HUFI-2; Leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2; leucine rich repeat (in FLII) interacting protein 2]
other names :
[leucine-rich repeat flightless-interacting protein 2 isoform 1; Leucine-rich repeat flightless-interacting protein 2; leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2; leucine rich repeat (in FLII) interacting protein 2]
products gene name :
[LRRFIP2]
other gene names :
[LRRFIP2; LRRFIP2; HUFI-2; LRR FLII-interacting protein 2]
uniprot entry name :
LRRF2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
721
specificity :
Three isoforms of LRRFIP2 are known to exist; this antibody will recognize all three. LRRFIP2 antibody is predicted to not cross-react with other LRRFIP family members.
purity :
LRRFIP2 Antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
LRRFIP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)
app notes :
LRRFIP2 antibody can be used for detection of LRRFIP2 by Western blot at 0.5 and 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL. Positive Control: MBS151749 Rat Colon Tissue Lysate. Optimal dilutions for each application to be determined by the researcher.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Conjugate: Unconjugated. Immunogen: LRRFIP2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRFIP2. The immunogen is located within amino acids 620-760 of LRRFIP2. Buffer: LRRFIP2 Antibody is supplied in PBS containing 0.02% sodium azide. Homology: Predicted species reactivity based on immunogen sequence: Bovine: (100%)
products description :
LRRFIP2 Antibody: The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF- B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.
ncbi gi num :
5453726
ncbi acc num :
NP_006300
ncbi gb acc num :
NM_006309.3
uniprot acc num :
Q9Y608
uniprot summary :
LRRFIP2: May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta- catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 3p22.2. Molecular Function: protein binding; LRR domain binding. Biological Process: Wnt receptor signaling pathway
size1 :
0.1 mg
price1 :
375 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!