catalog number :
MBS150632
products full name :
T-cadherin Antibody
products short name :
T-cadherin
products name syn :
T-cadherin; HB6; CD39L3; NTPDase-3; Ectonucleoside triphosphate diphosphohydrolase 3; CD39 antigen-like 3; NTPDase 3; ectonucleoside triphosphate diphosphohydrolase 3
other names :
Homo sapiens ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3), mRNA; Ectonucleoside triphosphate diphosphohydrolase 3; ectonucleoside triphosphate diphosphohydrolase 3; NTPDase 3; ecto-ATPase 3; ecto-ATPDase 3; ecto-apyrase 3; CD39 antigen-like 3; ecto-ATP diphosphohydrolase 3; ectonucleoside triphosphate diphosphohydrolase 3; CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPDase 3; Ecto-ATPase 3; Ecto-apyrase 3; HB6
products gene name :
ENTPD3
other gene names :
ENTPD3; ENTPD3; HB6; CD39L3; NTPDase-3; CD39L3; NTPDase 3; Ecto-ATPDase 3; Ecto-ATPase 3
uniprot entry name :
ENTP3_HUMAN
reactivity :
Human, Mouse
specificity :
At least two isoforms of T-cadherin are known to exist.
purity :
T-cadherin Antibody is affinity chromatography purified via peptide column.
storage stability :
T-cadherin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin. Buffer: T-cadherin Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.
ncbi gb acc num :
NM_001248.2
ncbi mol weight :
Predicted: 78; 84 kDa. Observed: 85 kDa
ncbi pathways :
Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!Purine Metabolism Pathway 82944!!Purine Metabolism Pathway 307!!Pyrimidine Metabolism Pathway 82946!!Pyrimidine Metabolism Pathway 309
ncbi summary :
This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]