catalog number :
MBS150520
products full name :
ARHGAP39 Antibody
products short name :
ARHGAP39
products name syn :
ARHGAP39; CrGAP; Vilse; KIAA1688; Rho GTPase-activating protein 39; Rho GTPase activating protein 39
other names :
rho GTPase-activating protein 39; Rho GTPase-activating protein 39; rho GTPase-activating protein 39; crossGAP homolog; RhoGAP93B homolog; Rho GTPase activating protein 39
products gene name :
ARHGAP39
other gene names :
ARHGAP39; ARHGAP39; CrGAP; Vilse; KIAA1688
uniprot entry name :
RHG39_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
ARHGAP39 antibody is predicted to not cross-react with other RhoGAP protein family members.
purity :
ARHGAP39 Antibody is affinity chromatography purified via peptide column.
storage stability :
ARHGAP39 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ARHGAP39 antibody can be used for detection of ARHGAP39 by Western blot at 1 - 2 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: ARHGAP39 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ARHGAP39. Buffer: ARHGAP39 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
ARHGAP39 Antibody: Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP39 (Rho GTPase activating protein 39) is a 1, 083 amino acid nuclear protein that contains one MyTH4 domain, one Rho GAP domain and two WW domains. It is encoded by a gene located on human chromosome 8, which is associated with a variety of diseases and malignancies. ARHGAP39 regulates robo signaling and plays important roles in axon guidance.
ncbi gb acc num :
NM_025251.1
ncbi mol weight :
125,029 Da
ncbi pathways :
Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); Inactivation Of Cdc42 And Rac Pathway (119529); Rho GTPase Cycle Pathway (106503); Signal Transduction Pathway (477114); Signaling By Rho GTPases Pathway (106502); Signaling By Robo Receptor Pathway (119527)
uniprot summary :
ARHGAP39: 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 8q24.3. Cellular Component: cytoskeleton; cytosol; nucleus. Biological Process: axon guidance; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction