antibody

Anosmin Antibody

MBS150502

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, immunocytochemistry, enzyme immunoassay

Antibody

Anosmin Antibody

Anosmin

Anosmin; HH1; HHA; KAL; KMS; ADMLX; WFDC19; KALIG-1; KALIG1; Anosmin-1; Adhesion molecule-like X-linked; Kallmann syndrome 1 sequence

anosmin-1; Anosmin-1; anosmin-1; kallmann syndrome protein; adhesion molecule-like X-linked; Kallmann syndrome interval gene 1; WAP four-disulfide core domain 19; Kallmann syndrome-1 sequence (anosmin-1); Kallmann syndrome 1 sequence; Adhesion molecule-like X-linked; Kallmann syndrome protein

KAL1

KAL1; KAL1; HH1; HHA; KAL; KMS; ADMLX; WFDC19; KALIG-1; ADMLX; KAL; KALIG1

KALM_HUMAN

Polyclonal

IgG

Rabbit

Human

680

Anosmin Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

Anosmin antibody can be stored at 4 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Anosmin antibody can be used for detection of Anosmin by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: Anosmin antibody was raised against an 18 amino acid synthetic peptide near the center of human Anosmin. Buffer: Anosmin Antibody is supplied in PBS containing 0.02% sodium azide.

Anosmin Antibody: Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.

119395746

NP_000207

NM_000216.2

P23352

76,112 Da

Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008]

0.1 mg

345 USD