catalog number :
MBS150444
products full name :
SUMO3 Antibody
products short name :
SUMO3
products name syn :
SUMO3; SMT3A; Smt3B; SMT3H1; SUMO-3; SMT3B; Small ubiquitin-related modifier 3; SMT3 homolog 1; SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
other names :
small ubiquitin-related modifier 3 isoform 1; Small ubiquitin-related modifier 3; small ubiquitin-related modifier 3; ubiquitin-like protein SMT3B; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 3; small ubiquitin-like modifier 3; SMT3 homolog 1; SUMO-2; Ubiquitin-like protein SMT3A
products gene name :
SUMO3
other gene names :
SUMO3; SUMO3; SMT3A; Smt3B; SMT3H1; SUMO-3; SUMO-3Curated
uniprot entry name :
SUMO3_HUMAN
reactivity :
Human, Mouse, Rat
purity :
SUMO3 Antibody is affinity chromatography purified via peptide column.
storage stability :
SUMO3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
SUMO3 antibody can be used for detection of SUMO3 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: SUMO3 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human SUMO3. Buffer: SUMO3 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
SUMO3 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (Sumo-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, which is a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. All SUMO proteins localize to the nucleus and are covalently conjugated, affecting protein structure, function and interactions. SUMO2 and 3 are 96% identical and are more mobile within nucleus relative to SUMO1. Specific functional differences between SUMO1 and SUMO2 and 3 remain to be identified.
ncbi gb acc num :
NM_006936.2
ncbi mol weight :
15,768 Da
ncbi pathways :
Diurnally Regulated Genes With Circadian Orthologs Pathway 198813!!Metabolism Of Proteins Pathway 106230!!Nuclear Pore Complex Pathway 470351!!Nuclear Pore Complex Pathway 890636!!Post-translational Protein Modification Pathway 161012!!Processing And Activation Of SUMO Pathway 833806!!RNA Transport Pathway 177876!!RNA Transport Pathway 175229!!SUMO Is Conjugated To E1 (UBA2:SAE1) Pathway 833808!!SUMO Is Proteolytically Processed Pathway 833807
ncbi summary :
This gene encodes a member of the small ubiquitin-related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post-translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants encoding distinct proteins have been described. [provided by RefSeq, Feb 2014]