product summary
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company name :
MyBioSource
product type :
antibody
product name :
NANOG Antibody
catalog :
MBS150440
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS150440
products type :
Antibody
products full name :
NANOG Antibody
products short name :
NANOG
products name syn :
NANOG; Homeobox protein NANOG; Homeobox transcription factor Nanog; hNanog; Nanog homeobox
other names :
Nanog homeobox, isoform CRA_a; Homeobox protein NANOG; homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox; Homeobox transcription factor Nanog; hNanog
products gene name :
NANOG
other gene names :
NANOG; NANOG; hNanog
uniprot entry name :
NANOG_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
305
purity :
NANOG Antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
NANOG antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
NANOG antibody can be used for detection of NANOG by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: NANOG antibody was raised against a 19 amino acid synthetic peptide near the center of human NANOG. Buffer: NANOG Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
NANOG Antibody: Expression of NANOG is required for the maintenance of pluripotency in epiblast and embryonic stem (ES) cells as well as for the ability to maintain ES self-renewal independently of LIF/Stat3. The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
ncbi gi num :
119609057
ncbi acc num :
EAW88651
uniprot acc num :
Q9H9S0
ncbi mol weight :
32,838 Da
ncbi pathways :
Cardiac Progenitor Differentiation Pathway 712094!!Developmental Biology Pathway 477129!!POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway 1127697!!POU5F1 (OCT4), SOX2, NANOG Repress Genes Related To Differentiation Pathway 1127698!!Proteoglycans In Cancer Pathway 782000!!Proteoglycans In Cancer Pathway 782054!!SIDS Susceptibility Pathways 198901!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1026136!!Signaling Pathways Regulating Pluripotency Of Stem Cells 1033502!!Transcriptional Regulation Of Pluripotent Stem Cells Pathway 1127696
size :
0.1 mg
price :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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