catalog number :
MBS150420
products full name :
ZFP219 Antibody
products short name :
ZFP219
products name syn :
ZFP219; ZFP219; Zinc finger protein 219; zinc finger protein 219
other names :
zinc finger protein 219; Zinc finger protein 219; zinc finger protein 219; zinc finger protein 219
products gene name :
ZNF219
other gene names :
ZNF219; ZNF219; ZFP219
uniprot entry name :
ZN219_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
At least two isoforms of ZFP219 are known to exist; this antibody will recognize both.
purity :
ZFP219 Antibody is affinity chromatography purified via peptide column.
storage stability :
ZFP219 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
ZFP219 antibody can be used for detection of ZFP219 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: ZFP219 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZFP219. Buffer: ZFP219 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
ZFP219 Antibody: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.
ncbi acc num :
NP_001095142
ncbi gb acc num :
NM_016423.2
ncbi mol weight :
76,877 Da