GALNT10 Antibody | MyBioSource MBS150336 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

GALNT10 Antibody

catalog :

MBS150336

quantity :

0.1 mg

price :

345 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS150336

products type :

Antibody

products full name :

GALNT10 Antibody

products short name :

GALNT10

products name syn :

GALNT10; GALNACT10; PPGALNACT10; PPGANTASE10; Polypeptide N-acetylgalactosaminyltransferase 10; Polypeptide GalNAc transferase 10; GalNAc-T10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)

other names :

polypeptide N-acetylgalactosaminyltransferase 10; Polypeptide N-acetylgalactosaminyltransferase 10; polypeptide N-acetylgalactosaminyltransferase 10; GalNAc transferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10); polypeptide N-acetylgalactosaminyltransferase 10; Polypeptide GalNAc transferase 10; GalNAc-T10; pp-GaNTase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10

products gene name :

GALNT10

other gene names :

GALNT10; GALNT10; GALNACT10; PPGALNACT10; PPGANTASE10; GalNAc-T10; pp-GaNTase 10

uniprot entry name :

GLT10_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

603

purity :

GALNT10 Antibody is affinity chromatography purified via peptide column.

form :

Liquid

concentration :

1 mg/mL

storage stability :

GALNT10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

app notes :

GALNT10 antibody can be used for detection of GALNT10 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

other info1 :

Conjugate: Unconjugated. Immunogen: GALNT10 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human GALNT10. Buffer: GALNT10 Antibody is supplied in PBS containing 0.02% sodium azide.

products description :

GALNT10 Antibody: Protein glycosylation is an important biological process that is carried out by a large family of glycosyltransferases that catalyze the synthesis of oligosaccharides and glycoconjugates. Polypeptide GalNAc transferases initiate the synthesis of mucin-type oligosaccharides by transferring GalNAc from UDP-GalNAc to the hydroxyl group of either a serine or threonine residue on the polypeptide acceptor. Polypeptide galactoaminyltransferase 10 (GALNT10) belongs to the polypeptide N-acetylgalactosaminyl-transferase (pp-GalNAc-T) protein family. Following expression in insect cells, recombinant GALNT10 showed significant GalNAcT activity toward mucin-derived peptides, and it utilized both non-glycosylated and glycosylated peptide substrates. GALNT10 mRNA is highly expressed in several distinct hypothalamic, thalamic, and amygdaloid nuclei in mouse brain. At least four isoforms of GALNT10 are known to exist.

ncbi gi num :

38195091

ncbi acc num :

NP_938080

ncbi gb acc num :

NM_198321.3

uniprot acc num :

Q86SR1

ncbi mol weight :

31,833 Da

ncbi pathways :

Metabolic Pathways (132956); Metabolism Of Proteins Pathway (106230); Mucin Type O-Glycan Biosynthesis Pathway (82977); Mucin Type O-Glycan Biosynthesis Pathway (347); O-glycan Biosynthesis, Mucin Type Core Pathway (413362); O-glycan Biosynthesis, Mucin Type Core Pathway (468249); O-linked Glycosylation Pathway (1127679); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012); Mucin Core 1 And Core 2 O-glycosylation Pathway (1108786)

ncbi summary :

This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]

uniprot summary :

GALNT10: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Transferase; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.41. Chromosomal Location of Human Ortholog: 5q33.2. Cellular Component: Golgi membrane; integral to membrane. Molecular Function: metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; carbohydrate binding. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification

size1 :

0.1 mg

price1 :

345 USD

more info or order :

MyBioSource product webpage