catalog number :
MBS150306
products full name :
CRISP2 Antibody
products short name :
CRISP2
products name syn :
CRISP2; CT36; TPX1; TSP1; GAPDL5; CRISP-2; Cysteine-rich secretory protein 2; Testis-specific protein TPX-1; cysteine-rich secretory protein 2
other names :
cysteine-rich secretory protein 2; Cysteine-rich secretory protein 2; cysteine-rich secretory protein 2; cancer/testis antigen 36; testis-specific protein TPX-1; testis specific protein 1 (probe H4-1 p3-1); glyceraldehyde-3-phosphate dehydrogenase-like 5; cysteine-rich secretory protein 2; Cancer/testis antigen 36; CT36; Testis-specific protein TPX-1
products gene name :
CRISP2
other gene names :
CRISP2; CRISP2; CT36; TPX1; TSP1; GAPDL5; CRISP-2; GAPDL5; TPX1; CRISP-2; CT36
uniprot entry name :
CRIS2_HUMAN
purity :
CRISP2 Antibody is affinity chromatography purified via peptide column.
storage stability :
CRISP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
CRISP2 antibody can be used for detection of CRISP2 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: CRISP2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CRISP2. Buffer: CRISP2 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
CRISP2 Antibody: The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.
ncbi acc num :
NP_001135880
ncbi gb acc num :
NM_001142408.2
ncbi mol weight :
31,581 Da