catalog number :
MBS150296
products full name :
ZBTB1 Antibody
products short name :
ZBTB1
products name syn :
ZBTB1; ZNF909; KIAA0997; Zinc finger and BTB domain-containing protein 1; zinc finger and BTB domain containing 1
other names :
ZBTB1 protein; Zinc finger and BTB domain-containing protein 1; zinc finger and BTB domain-containing protein 1; zinc finger and BTB domain containing 1
products gene name :
ZBTB1
other gene names :
ZBTB1; ZBTB1; ZNF909; KIAA0997
uniprot entry name :
ZBTB1_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
At least two isoforms of ZBTB1 are known to exist. This ZBTB1 antibody will not cross-react with ZBTB2.
purity :
ZBTB1 Antibody is affinity chromatography purified via peptide column.
storage stability :
ZBTB1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ZBTB1 antibody can be used for detection of ZBTB1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: ZBTB1 antibody was raised against a 14 amino acid synthetic peptide near the center of human ZBTB1. Buffer: ZBTB1 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
ZBTB1 Antibody: ZBTB1 is a zinc finger protein that also contains BTB (BR-C, ttk and bab) domain. While little is known about this protein or the related protein ZBTB2, its expression is known to be down-regulated in human bronchial epithelial cells in response to the presence of Vanadium. Recently, expression of variant ZBTB1 protein has been associated with increased age-related macular degeneration.
ncbi mol weight :
73,682 Da
uniprot summary :
ZBTB1: May be involved in transcriptional regulation. 2 isoforms of the human protein are produced by alternative splicing. Protein type: C2H2-type zinc finger protein. Chromosomal Location of Human Ortholog: 14q23.3. Cellular Component: nucleoplasm; nuclear body; nucleus. Molecular Function: protein homodimerization activity; DNA binding; protein heterodimerization activity; metal ion binding. Biological Process: positive regulation of natural killer cell differentiation; thymus development; positive regulation of T cell differentiation; B cell differentiation; T cell differentiation in the thymus; innate immune response; positive regulation of T cell mediated immunity; negative regulation of transcription from RNA polymerase II promoter; mRNA transcription from RNA polymerase II promoter; protein homooligomerization