catalog number :
MBS150294
products full name :
TSLP Receptor Antibody
products short name :
TSLP Receptor
products name syn :
TSLP Receptor; CRLM2; Ly114; Tpte2; Tslpr; Crlm2; Cytokine receptor-like factor 2; Cytokine receptor-like molecule 2; CRLM-2; cytokine receptor-like factor 2
other names :
cytokine receptor-like factor 2; Cytokine receptor-like factor 2; cytokine receptor-like factor 2; CRLM-2; delta 1; TSLP receptor; lymphocyte antigen 114; type I cytokine receptor delta 1; cytokine receptor-like molecule 2; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin, receptor; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2; cytokine receptor-like factor 2; Cytokine receptor-like molecule 2; CRLM-2; Thymic stromal lymphopoietin protein receptor; TSLP receptor; Type I cytokine receptor delta 1
products gene name :
Crlf2
other gene names :
Crlf2; Crlf2; CRLM2; Ly114; Tpte2; Tslpr; Crlm2; Tpte2; Tslpr; CRLM-2; TSLP receptor
uniprot entry name :
CRLF2_MOUSE
purity :
TSLP Receptor Antibody is affinity chromatography purified via peptide column.
storage stability :
TSLP Receptor antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
TSLP-R antibody can be used for detection of TSLP-R by Western blot at 0.5 - 1 mug/mL. Despite its predicted molecular weight, TSLP-R often migrates at a higher molecular weight in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: TSLP Receptor antibody was raised against a 19 amino acid synthetic peptide from near the center of human TSLP receptor. Buffer: TSLP Receptor Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
TSLP Receptor Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.
ncbi gb acc num :
NM_016715.3
ncbi mol weight :
13,236 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Jak-STAT Signaling Pathway 83274!!Jak-STAT Signaling Pathway 488