catalog number :
MBS150213
products full name :
TMEM59 Antibody
products short name :
TMEM59
products name syn :
TMEM59; C1orf8; HSPC001; C1orf8; UNQ169/PRO195; Transmembrane protein 59; Liver membrane-bound protein; transmembrane protein 59
other names :
transmembrane protein 59; Transmembrane protein 59; transmembrane protein 59; liver membrane-bound protein; transmembrane protein 59; Liver membrane-bound protein
products gene name :
TMEM59
other gene names :
TMEM59; TMEM59; C1orf8; HSPC001; C1orf8
uniprot entry name :
TMM59_HUMAN
purity :
TMEM59 Antibody is affinity chromatography purified via peptide column.
storage stability :
TMEM59 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
TMEM59 antibody can be used for detection of TMEM59 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: TMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59. Buffer: TMEM59 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
TMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
ncbi gb acc num :
NM_004872.3
ncbi mol weight :
36,223 Da