antibody

DLK1 Antibody

MBS150208

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunocytochemistry, enzyme immunoassay

Antibody

DLK1 Antibody

DLK1

DLK1; DLK; Protein delta homolog 1; pG2; DLK-1; delta-like 1 homolog (Drosophila)

protein delta homolog 1; Protein delta homolog 1; protein delta homolog 1; secredeltin; fetal antigen 1; preadipocyte factor 1; delta-like 1 homolog (Drosophila); pG2Fetal antigen 1; FA1

DLK1

DLK1; DLK1; DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; DLK; DLK-1; FA1

DLK1_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

383

At least four isoforms of DLK1 are known to exist.

DLK1 Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

DLK1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

DLK1 antibody can be used for detection of DLK1 by Western blot at 1 - 2 mug/mL.

Conjugate: Unconjugated. Immunogen: DLK1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human DLK1. Buffer: DLK1 Antibody is supplied in PBS containing 0.02% sodium azide.

DLK1 Antibody: The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.

74136023

NP_003827

NM_003836.5

P80370

42 kDa

Activated NOTCH1 Transmits Signal To The Nucleus Pathway 576270!!Adipogenesis Pathway 198832!!Disease Pathway 530764!!FBXW7 Mutants And NOTCH1 In Cancer Pathway 771596!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Notch Signaling Pathway 169345!!Signal Transduction Pathway 477114!!Signaling By NOTCH Pathway 106485!!Signaling By NOTCH1 Pathway 576269!!Signaling By NOTCH1 HD Domain Mutants In Cancer Pathway 771590

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]

0.1 mg

345 USD