catalog number :
MBS150181
products full name :
MIPU1 Antibody
products short name :
MIPU1
products name syn :
MIPU1; MIPU1; Zinc finger protein 667; zinc finger protein 667
other names :
zinc finger protein 667; Zinc finger protein 667; zinc finger protein 667; myocardial ischemic preconditioning upregulated 1 ortholog; zinc finger protein 667
products gene name :
ZNF667
other gene names :
ZNF667; ZNF667; MIPU1
uniprot entry name :
ZN667_HUMAN
reactivity :
Human, Mouse, Rat
purity :
MIPU1 Antibody is affinity chromatography purified via peptide column.
storage stability :
MIPU1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
MIPU1 antibody can be used for detection of MIPU1 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: MIPU1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human MIPU1. Buffer: MIPU1 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
MIPU1 Antibody: Mipu1, also known as zinc finger protein 667 or ZNF667, encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain. This protein is highly expressed in heart and brain and is upregulated in rat heart after a transient ischemia-reperfusion procedure. Overexpression experiments suggest that Mipu1 suppresses the transcriptional activities of AP-1 and SRE in the MAPK signaling pathway and thus may play a role in the pathogenesis of cardiac and vascular disease. At least four isoforms of MIPU1 are known to exist.
ncbi gb acc num :
NM_022103.2
ncbi mol weight :
70,161 Da
ncbi pathways :
Gene Expression Pathway (105937); Generic Transcription Pathway (105938)
uniprot summary :
ZNF667: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. Protein type: C2H2-type zinc finger protein. Chromosomal Location of Human Ortholog: 19q13.43. Cellular Component: nucleus. Molecular Function: DNA binding; metal ion binding; transcription cofactor activity. Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent