antibody

DRGX Antibody

MBS150180

0.1 mg

345 USD

polyclonal

chicken

nonconjugated

human, rat

western blot, ELISA, immunocytochemistry, enzyme immunoassay

Antibody

DRGX Antibody

DRGX

DRGX; DRG11; PRRXL1; Dorsal root ganglia homeobox protein; Paired-related homeobox protein-like 1; dorsal root ganglia homeobox

Dorsal root ganglia homeobox protein; dorsal root ganglia homeobox protein; dorsal root ganglia homeobox; Paired-related homeobox protein-like 1

DRGX

DRGX; DRGX; DRG11; PRRXL1; PRRXL1

DRGX_HUMAN

Polyclonal

IgY

Chicken

Human, Mouse, Rat

263

At least two are known to exist; DRGX antibody is predicted to not cross-react with other Homeodomain proteins.

DRGX Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

DRGX antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

DRGX antibody can be used for detection of DRGX by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunofluorescence starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: DRGX antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human DRGX. Buffer: DRGX Antibody is supplied in PBS containing 0.02% sodium azide.

DRGX Antibody: DRGX, also known as DRG11 or PRRXL1, is a paired homeodomain transcription factor, and was initially cloned from a differential hybridization screen aimed at identifying dorsal root ganglia (DRG)-specific genes. DRGX is a key regulator of the differentiation of the spinal cord neuronal circuit dedicated to the processing of nociceptive information. DRGX is also important for the formation of the whisker-related somatosensory maps in the principal sensory nucleus of the trigeminal nerve, thalamus and somatosensory cortex.

122937484

NP_001073989

NM_001080520.1

A6NNA5

28,672 Da

DRGX: Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain. Belongs to the paired homeobox family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 10q11.23. Cellular Component: nucleus. Molecular Function: sequence-specific DNA binding. Biological Process: dorsal spinal cord development; detection of temperature stimulus; axon guidance; trigeminal nerve development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; neuron migration; detection of chemical stimulus; sensory perception of mechanical stimulus

0.1 mg

345 USD