catalog number :
MBS150170
products full name :
RGPD5 Antibody
products short name :
RGPD5
products name syn :
RGPD5; BS63; RGP5; BS-63; HEL161; RANBP2L1; RGP7; RGPD7; RGPD6; RANBP2L2; RGP6; Sperm membrane protein BS-63; RanBP2L1; RANBP2-like and GRIP domain containing 5
other names :
RANBP2-like and GRIP domain-containing protein 5/6 isoform 1; RANBP2-like and GRIP domain-containing protein 5/6; RANBP2-like and GRIP domain-containing protein 5/6; ranBP2L1; ranBP2-like 1; ranBP2-like 1/2; ran-binding protein 2-like 1; sperm membrane protein BS-63; epididymis luminal protein 161; ran-binding protein 2-like 1/2; RANBP2-like and GRIP domain containing 5; Ran-binding protein 2-like 1/2; RanBP2-like 1/2; RanBP2L1; RanBP2L2; Sperm membrane protein BS-63
products gene name :
RGPD5
other gene names :
RGPD5; RGPD5; BS63; RGP5; BS-63; HEL161; RANBP2L1; RGP5; RGP7; RGPD7; RanBP2-like 1/2; RanBP2L1; RanBP2L2
uniprot entry name :
RGPD5_HUMAN
purity :
RGPD5 Antibody is affinity chromatography purified via peptide column.
storage stability :
RGPD5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
RGPD5 antibody can be used for detection of RGPD5 by Western blot at 1 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: RGPD5 antibody was raised against a 23 amino acid synthetic peptide from near the center of human RGPD5. Buffer: RGPD5 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
RGPD5 Antibody: The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.
ncbi gb acc num :
NM_005054.2
ncbi mol weight :
103,334 Da
ncbi summary :
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene shares a high degree of sequence identity with RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2. Alternative splicing has been observed for this locus and two variants are described. Additional splicing is suggested but complete sequence for further transcripts has not been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
RGPD5/6: 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 2q13. Cellular Component: cytoplasm. Biological Process: protein targeting to Golgi