BAFF Antibody | MyBioSource MBS150169 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

BAFF Antibody

catalog :

MBS150169

quantity :

0.1 mg

price :

345 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS150169

products type :

Antibody

products full name :

BAFF Antibody

products short name :

BAFF

products name syn :

BAFF; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; UNQ401/PRO738; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; tumor necrosis factor (ligand) superfamily, member 13b

other names :

tumor necrosis factor ligand superfamily member 13B isoform 1; Tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor ligand superfamily member 13B; delta BAFF; Delta4 BAFF; B-lymphocyte stimulator; B-cell-activating factor; ApoL related ligand TALL-1; TNF homolog that activates apoptosis; dendritic cell-derived TNF-like molecule; tumor necrosis factor-like protein ZTNF4; TNF and ApoL-related leukocyte expressed ligand 1; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor (ligand) superfamily, member 13b; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD_antigen: CD257Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form

products gene name :

TNFSF13B

other gene names :

TNFSF13B; TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1

uniprot entry name :

TN13B_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

285

purity :

BAFF Antibody is Ion exchange chromatography purified.

form :

Liquid

concentration :

1 mg/mL

storage stability :

BAFF antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

tested application :

ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)

app notes :

BAFF antibody can be used for detection of BAFF by Western blot a 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 1 mug/mL.

other info1 :

Conjugate: Unconjugated. Immunogen: BAFF antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human BAFF. Buffer: BAFF Antibody is supplied in PBS containing 0.02% sodium azide.

products description :

BAFF Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF- B and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis.

ncbi gi num :

5730097

ncbi acc num :

NP_006564

ncbi gb acc num :

NM_006573.4

uniprot acc num :

Q9Y275

ncbi mol weight :

31 kDa

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Intestinal Immune Network For IgA Production Pathway 128760!!Intestinal Immune Network For IgA Production Pathway 128670!!NF-kappa B Signaling Pathway 634527!!Rheumatoid Arthritis Pathway 200309!!Rheumatoid Arthritis Pathway 200269!!Spinal Cord Injury Pathway 739007

ncbi summary :

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

size :

0.1 mg

price :

345 USD

more info or order :

MyBioSource product webpage