This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Survivin Antibody
catalog :
MBS150166
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS150166
products type :
Antibody
products full name :
Survivin Antibody
products short name :
Survivin
products name syn :
Survivin; API4; EPR-1; API4; IAP4; Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; baculoviral IAP repeat-containing 5
other names :
baculoviral IAP repeat-containing protein 5 isoform 1; Baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat-containing protein 5; apoptosis inhibitor 4; survivin variant 3 alpha; apoptosis inhibitor survivin; baculoviral IAP repeat containing 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin
products gene name :
BIRC5
other gene names :
BIRC5; BIRC5; API4; EPR-1; API4; IAP4
uniprot entry name :
BIRC5_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
sequence length :
142
purity :
Survivin Antibody is affinity chromatography purified via peptide column.
form :
Liquid
storage stability :
mSurvivin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
mSurvivin antibody can be used for detection of survivin by Western blot at 1 mug/mL. An approximate 17 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: Survivin antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of mouse Survivin. Buffer: Survivin Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
Survivin Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP. Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.
ncbi gi num :
59859878
ncbi acc num :
NP_001159
ncbi gb acc num :
NM_001168.2
uniprot acc num :
O15392
ncbi mol weight :
17 kDa
ncbi pathways :
Apoptosis Pathway 198797!!Apoptosis Modulation And Signaling Pathway 198822!!Aurora A Signaling Pathway 137925!!Aurora B Signaling Pathway 138080!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Colorectal Cancer Pathway 83106!!Colorectal Cancer Pathway 518!!FOXM1 Transcription Factor Network Pathway 137935!!Hepatitis B Pathway 694606
ncbi summary :
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
size :
0.1 mg
price :
345 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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