antibody

SCARB1 Antibody

MBS150134

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

SCARB1 Antibody

SCARB1

SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; CLA1; Scavenger receptor class B member 1; CD36 and LIMPII analogous 1; scavenger receptor class B, member 1

Scavenger receptor class B member 1; Scavenger receptor class B member 1; scavenger receptor class B member 1; CD36 and LIMPII analogous 1; scavenger receptor class B type III; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; scavenger receptor class B, member 1; CD36 and LIMPII analogous 1; CLA-1; CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; SR-BI; CD_antigen: CD36

SCARB1

SCARB1; SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; CD36L1; CLA1; SRB1; CLA-1

SCRB1_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

552

SCARB1 Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

SCARB1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

SCARB1 antibody can be used for detection of SCARB1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: SCARB1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SCARB1. Buffer: SCARB1 Antibody is supplied in PBS containing 0.02% sodium azide.

SCARB1 Antibody: Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.

37999904

Q8WTV0.1

Q8WTV0

56,170 Da

Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Fat Digestion And Absorption Pathway 194385!!Fat Digestion And Absorption Pathway 194324!!Folate Metabolism Pathway 198833!!HDL-mediated Lipid Transport Pathway 106158!!Hepatitis C Pathway 173973!!Hepatitis C Pathway 173907!!Lipid Digestion, Mobilization, And Transport Pathway 106111

The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

0.1 mg

345 USD