antibody

TFF3 Antibody

MBS150083

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

TFF3 Antibody

TFF3

TFF3; ITF; P1B; TFI; ITF; Trefoil factor 3; Intestinal trefoil factor; hITF; trefoil factor 3 (intestinal)

trefoil factor 3 (intestinal), isoform CRA_b; Trefoil factor 3; trefoil factor 3; polypeptide P1.B; trefoil factor 3 (intestinal); Intestinal trefoil factor; hITF; Polypeptide P1.B; hP1.B

TFF3

TFF3; TFF3; ITF; P1B; TFI; ITF; TFI; hITF; hP1.B

TFF3_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

137

TFF3 antibody is predicted to not cross-react with other TFF family members.

TFF3 Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

TFF3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

TFF3 antibody can be used for detection of TFF3 by Western blot at 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: TFF3 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human TFF3. Buffer: TFF3 Antibody is supplied in PBS containing 0.02% sodium azide.

TFF3 Antibody: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.

119629977

NP_003217

Q07654

Predicted: 10 kDa. Observed: 11 kDa

HIF-1-alpha Transcription Factor Network Pathway 138045!!IL4-mediated Signaling Events Pathway 137933

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

0.1 mg

345 USD