antibody

SARM Antibody

MBS150071

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

human, mouse

western blot, ELISA, immunocytochemistry, enzyme immunoassay

Antibody

SARM Antibody

SARM

SARM; SARM; SAMD2; MyD88-5; KIAA0524; SARM; Sterile alpha and TIR motif-containing protein 1; Sterile alpha and Armadillo repeat protein; sterile alpha and TIR motif containing 1

sterile alpha and TIR motif-containing protein 1; Sterile alpha and TIR motif-containing protein 1; sterile alpha and TIR motif-containing protein 1; tir-1 homolog; SAM domain-containing protein 2; sterile alpha and Armadillo repeat protein; sterile alpha motif domain-containing protein 2; sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila; sterile alpha and TIR motif containing 1; Sterile alpha and Armadillo repeat protein; Sterile alpha motif domain-containing protein 2; MyD88-5; SAM domain-containing protein 2; Tir-1 homolog

SARM1

SARM1; SARM1; SARM; SAMD2; MyD88-5; KIAA0524; SAMD2; SARM; MyD88-5; SAM domain-containing protein 2

SARM1_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse

724

SARM Antibody is Ion exchange chromatography purified.

Liquid

1 mg/mL

SARM antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

SARM antibody can be used for detection of SARM by Western blot at 0.5 to 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 2 mug/mL. For immunofluorescence start at 2 mug/mL.

Conjugate: Unconjugated. Immunogen: SARM antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human SARM. Buffer: SARM Antibody is supplied in PBS containing 0.02% sodium azide.

SARM Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF- B, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.

154090976

NP_055892

NM_015077.3

Q6SZW1

75,337 Da

Activated TLR4 Signalling Pathway 106400!!Activation Of IRF3/IRF7 Mediated By TBK1/IKK Epsilon Pathway 187088!!IKK Complex Recruitment Mediated By RIP1 Pathway 187090!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!MyD88-independent Cascade Pathway 106401!!TRAF6 Mediated Induction Of TAK1 Complex Pathway 187091!!TRIF-mediated TLR3/TLR4 Signaling Pathway 187089!!Toll Like Receptor 3 (TLR3) Cascade Pathway 106391!!Toll Like Receptor 4 (TLR4) Cascade Pathway 106398

0.1 mg

345 USD