catalog number :
MBS1498738
products full name :
TMEM55A Antibody
products short name :
[TMEM55A]
products name syn :
[Type 2 phosphatidylinositol 4; 5-bisphosphate 4-phosphatase (EC:3.1.3.78); Type 2 PtdIns-4; 5-P2 4-Ptase; TMEM55A; PtdIns-4; 5-P2 4-Ptase II; Transmembrane protein 55A]
other names :
[type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; transmembrane protein 55A; PtdIns-4,5-P2 4-Ptase II; Transmembrane protein 55A]
products gene name :
[TMEM55A]
other gene names :
[TMEM55A; TMEM55A; Type 2 PtdIns-4,5-P2 4-Ptase]
uniprot entry name :
TM55A_HUMAN
reactivity :
Human, Mouse
purity :
>95%, Protein G Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Recommended dilution: WB:1:500-2000. IHC:1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant human Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase protein. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-87457 / sc-87458
products description :
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.
ncbi acc num :
NP_061180.1
ncbi gb acc num :
NM_018710.2
ncbi mol weight :
28,081 Da
ncbi pathways :
3-phosphoinositide Degradation Pathway (545349); 3-phosphoinositide Degradation Pathway (139488); D-myo-inositol-5-phosphate Metabolism Pathway (545315); D-myo-inositol-5-phosphate Metabolism Pathway (138601); Phosphatidylinositol Signaling System Pathway (83052); Phosphatidylinositol Signaling System Pathway (461); Superpathway Of Inositol Phosphate Compounds (547492)
ncbi summary :
TMEM55A catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008]
uniprot summary :
TMEM55A: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate. Protein type: Membrane protein, integral; Membrane protein, multi-pass; EC 3.1.3.78; Phosphatase, lipid. Chromosomal Location of Human Ortholog: 8q21.3. Cellular Component: integral to membrane; late endosome membrane; lysosomal membrane. Biological Process: phosphoinositide dephosphorylation