catalog number :
MBS1496526
products full name :
Rabbit anti-human Aldo-keto reductase family 1 member B10 polyclonal Antibody(AKR1B10)
products short name :
[Aldo-keto reductase family 1 member B10]
products name syn :
[Aldo-keto reductase family 1 member B10 (EC 1.1.1.-) (ARL-1) (Aldosereductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Smallintestine reductase) (SI reductase), AKR1B10, AKR1B11]
other names :
[aldo-keto reductase family 1 member B10; Aldo-keto reductase family 1 member B10; aldo-keto reductase family 1 member B10; aldo-keto reductase family 1, member B10 (aldose reductase); ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase]
products gene name :
[AKR1B10]
other gene names :
[AKR1B10; AKR1B10; HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12; AKR1B11; ARP; hARP; SI reductase]
uniprot entry name :
AK1BA_HUMAN
purity :
Antigen Affinity Purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB:1:200-1000. IHC:1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Research Area: Signal Transduction. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant human Aldo-keto reductase family 1 member B10 protein (1-316aa). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54256 / sc-54352 / sc-135334
products description :
Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
ncbi acc num :
NP_064695.3
ncbi gb acc num :
NM_020299.4
ncbi pathways :
Fructose And Mannose Metabolism Pathway (82930); Fructose And Mannose Metabolism Pathway (291); Galactose Metabolism Pathway (82931); Galactose Metabolism Pathway (292); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Fat-soluble Vitamins Pathway (1339147); Metabolism Of Vitamins And Cofactors Pathway (1270144)
ncbi summary :
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
uniprot summary :
AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family. Protein type: EC 1.1.1.21; EC 1.1.1.-; Oxidoreductase; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - butanoate; Lipid Metabolism - linoleic acid. Chromosomal Location of Human Ortholog: 7q33. Cellular Component: cytosol; lysosome. Molecular Function: aldo-keto reductase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; protein binding; retinal dehydrogenase activity. Biological Process: aldehyde metabolic process; digestion; farnesol catabolic process; fat-soluble vitamin metabolic process; phototransduction, visible light; retinoid metabolic process; steroid metabolic process; vitamin metabolic process