Rabbit anti-human Anti-Muellerian hormone type-2 receptor polyclonal Antibody(AMHR2) | MyBioSource MBS1496327 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti-human Anti-Muellerian hormone type-2 receptor polyclonal Antibody(AMHR2)

catalog :

MBS1496327

quantity :

0.05 mL

price :

120 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot. All lanes: Anti-Muellerian hormone type-2 receptor antibody at 15ug/ml+mouse brain tissue. Secondary. Goat polyclonal to rabbit at 1/10000 dilution. Predicted band size: 63,53,52 kDa. Observed band size: 63 kDa.

image 2 :

Immunohistochemistry of paraffin-embedded human testis using MBS1496327 at dilution 1:100

product information

catalog number :

MBS1496327

products type :

Antibody

products full name :

Rabbit anti-human Anti-Muellerian hormone type-2 receptor polyclonal Antibody(AMHR2)

products short name :

[Anti-Muellerian hormone type-2 receptor]

products name syn :

[Anti-Muellerian hormone type II receptor; AMH type II receptor; MIS type II receptor; MISRII; MRII; AMHR2; AMHR; MISR2]

other names :

[anti-Muellerian hormone type-2 receptor isoform 2; Anti-Muellerian hormone type-2 receptor; anti-Muellerian hormone type-2 receptor; anti-Mullerian hormone receptor type II; Anti-Muellerian hormone type II receptor; AMH type II receptor; MIS type II receptor; MISRII; MRII]

products gene name :

[AMHR2]

other gene names :

[AMHR2; AMHR2; AMHR; MRII; MISR2; MISRII; AMHR; MISR2; AMH type II receptor; MISRII; MRII]

uniprot entry name :

AMHR2_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse

sequence length :

478

purity :

Antigen Affinity Purified

form :

Liquid; PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

storage stability :

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemmistry (IHC)

app notes :

Recommended dilution:. WB: 1:500-2000. IHC: 1:20-1:200

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Conjugate: Non-conjugated. Species: Human. Research Area: Signal Transduction

other info2 :

Immunogen: Recombinant human Anti-Muellerian hormone type-2 receptor protein(18-149aa). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66546 / sc-67287

products description :

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

ncbi gi num :

257743467

ncbi acc num :

NP_001158162.1

ncbi gb acc num :

NM_001164690.1

uniprot acc num :

Q16671

ncbi pathways :

ALK2 Signaling Events Pathway (137983); BMP Signaling Pathway (1084755); BMP Signaling Pathway (1108218); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)

ncbi summary :

This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]

uniprot summary :

MISR2: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. Protein type: Protein kinase, Ser/Thr (receptor); Membrane protein, integral; Protein kinase, TKL; EC 2.7.11.30; Kinase, protein; TKL group; STKR family; Type2 subfamily. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: integral to plasma membrane. Molecular Function: ATP binding; hormone binding; metal ion binding; protein binding; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta receptor activity, type II. Biological Process: female gonad development; male gonad development; Mullerian duct regression; sex differentiation; signal transduction; transforming growth factor beta receptor signaling pathway. Disease: Persistent Mullerian Duct Syndrome, Types I And Ii

size1 :

0.05 mL

price1 :

120 USD

size2 :

0.1 mL

price2 :

160

more info or order :

MyBioSource product webpage