product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human Sterol O-acyltransferase 1 polyclonal Antibody(SOAT1)
catalog :
MBS1495845
quantity :
0.05 mL
price :
120 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS1495845 image 1
All lanes: Sterol O-acyltransferase 1 antibody at 2ug/ml. Lane 1:293T whole cell lysate. Lane 2:jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit at 1/10000 dilution. Predicted band size: 65,59,58 kDa. Observed band size: 65 kDa.
image 2 :
MyBioSource MBS1495845 image 2
Immunohistochemistry of paraffin-embedded human placenta using MBS1495845 at dilution 1:100
product information
catalog number :
MBS1495845
products type :
Antibody
products full name :
Rabbit anti-human Sterol O-acyltransferase 1 polyclonal Antibody(SOAT1)
products short name :
[Sterol O-acyltransferase 1]
products name syn :
[Acyl-coenzyme A:cholesterol acyltransferase 1; ACAT-1; Cholesterol acyltransferase 1; SOAT1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT]
other names :
[sterol O-acyltransferase 1 isoform 2; Sterol O-acyltransferase 1; sterol O-acyltransferase 1; sterol O-acyltransferase 1; Acyl-coenzyme A:cholesterol acyltransferase 1; ACAT-1; Cholesterol acyltransferase 1]
products gene name :
[SOAT1]
other gene names :
[SOAT1; SOAT1; ACAT; SOAT; STAT; ACACT; ACAT1; ACAT-1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT; ACAT-1]
uniprot entry name :
SOAT1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
492
purity :
Antigen Affinity Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB:1:500-2000. IHC:1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant human Sterol O-acyltransferase 1 protein (1-130aa). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21030 / sc-21028 / sc-21029 / sc-20951
products description :
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.
ncbi gi num :
357430782
ncbi acc num :
NP_001239440.1
ncbi gb acc num :
NM_001252511.1
uniprot acc num :
P35610
ncbi mol weight :
57,238 Da
ncbi pathways :
Statin Pathway (198852); Steroid Biosynthesis Pathway (82937); Steroid Biosynthesis Pathway (298)
ncbi summary :
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
uniprot summary :
SOAT1: Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily. Protein type: Membrane protein, integral; Lipid Metabolism - steroid biosynthesis; EC 2.3.1.26; Transferase; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 1q25. Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane. Molecular Function: acyl-CoA binding; cholesterol binding; protein binding; sterol O-acyltransferase activity. Biological Process: cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; positive regulation of amyloid precursor protein biosynthetic process
size1 :
0.05 mL
price1 :
120 USD
size2 :
0.1 mL
price2 :
160
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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