product summary
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company name :
MyBioSource
product type :
antibody
product name :
FPR1 Antibody, HRP conjugated
catalog :
MBS1494366
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1494366
products type :
Antibody
products full name :
FPR1 Antibody, HRP conjugated
products short name :
[FPR1]
products name syn :
[fMet-Leu-Phe receptor; fMLP receptor; FPR1; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor]
other names :
[fMet-Leu-Phe receptor; fMet-Leu-Phe receptor; fMet-Leu-Phe receptor; formyl peptide receptor 1; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor]
products gene name :
[FPR1]
other gene names :
[FPR1; FPR1; FPR; FMLP; fMLP receptor; FPR]
uniprot entry name :
FPR1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
purity :
>95%, Protein G Purified
form :
Liquid
storage stability :
Upon receipt. aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP. Immunogen: Recombinant Human fMet-Leu-Phe receptor protein (306-350AA). Species: Homo sapiens (Human). Research Area: Immunology
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30016
products description :
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1712023, PubMed:10514456).
ncbi gi num :
300863094
ncbi acc num :
NP_001180235.1
ncbi gb acc num :
NM_001193306.1
uniprot acc num :
P21462
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway (1269551); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Peptide GPCRs Pathway (920907); Peptide GPCRs Pathway (198897)
ncbi summary :
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
uniprot summary :
FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: endosome; integral to membrane; plasma membrane. Molecular Function: N-formyl peptide receptor activity; protein binding; RAGE receptor binding; receptor activity. Biological Process: activation of MAPK activity; cell motility; chemotaxis; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); nitric oxide mediated signal transduction; signal transduction
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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