catalog number :
MBS1493737
products full name :
Rabbit anti-human Serine/arginine-rich splicing factor 4 polyclonal Antibody(SRSF4)
products short name :
[Serine/arginine-rich splicing factor 4]
products name syn :
[Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4), SRSF4, SFRS4 SRP75]
other names :
[serine/arginine-rich splicing factor 4; Serine/arginine-rich splicing factor 4; serine/arginine-rich splicing factor 4; serine/arginine-rich splicing factor 4; Pre-mRNA-splicing factor SRP75; SRP001LB; Splicing factor, arginine/serine-rich 4]
products gene name :
[SRSF4]
other gene names :
[SRSF4; SRSF4; SFRS4; SRP75; SFRS4; SRP75]
uniprot entry name :
SRSF4_HUMAN
purity :
Antigen Affinity Purified
storage stability :
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB:1:200-1000. IHC:1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Conjugate: Non-conjugated. Research Area: Epigenetics and Nuclear Signaling
other info2 :
Immunogen: Recombinant human Serine/arginine-rich splicing factor 4 protein (1-180aa). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28721
products description :
Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.
ncbi acc num :
NP_005617.2
ncbi gb acc num :
NM_005626.4
ncbi pathways :
Cleavage Of Growing Transcript In The Termination Region Pathway (1269686); Gene Expression Pathway (1269649); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Processing Of Capped Intron-Containing Pre-mRNA Pathway (1269688); RNA Polymerase II Transcription Pathway (1269675); RNA Polymerase II Transcription Termination Pathway (1269685); Spliceosome Pathway (125136); Spliceosome Pathway (124832); Transport Of Mature Transcript To Cytoplasm Pathway (1269693)
ncbi summary :
This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009]
uniprot summary :
SFRS4: Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. Protein type: RNA splicing; RNA-binding; Spliceosome. Chromosomal Location of Human Ortholog: 1p35.3. Cellular Component: nuclear speck; nucleoplasm; nucleus. Molecular Function: nucleotide binding. Biological Process: gene expression; hemopoietic progenitor cell differentiation; mRNA 3'-end processing; mRNA export from nucleus; mRNA processing; negative regulation of nuclear mRNA splicing, via spliceosome; nuclear mRNA splicing, via spliceosome; RNA splicing; RNA splicing, via transesterification reactions; termination of RNA polymerase II transcription; transcription from RNA polymerase II promoter