catalog number :
MBS1493076
products full name :
Rabbit anti-Human coronavirus OC43 Spike glycoprotein polyclonal Antibody
products short name :
[coronavirus OC43 Spike glycoprotein]
products name syn :
[E2; Peplomer protein; S; 3]
other names :
[S protein; Spike glycoprotein; spike surface glycoprotein; E2; Peplomer protein]
other gene names :
[S; S; S glycoprotein]
uniprot entry name :
SPIKE_CVHOC
reactivity :
Human Coronavirus OC43
purity :
Caprylic Acid Ammonium Sulfate Precipitation
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant Human coronavirus OC43 Spike glycoprotein protein(15-344aa)
products description :
S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
ncbi acc num :
NP_937950.1
ncbi gb acc num :
NC_005147.1
ncbi mol weight :
150,089 Da
uniprot summary :
S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection.