catalog number :
MBS1492400
products full name :
Rabbit anti-human C-type lectin domain family 12 member A polyclonal Antibody(CLEC12A)
products short name :
[C-type lectin domain family 12 member A]
products name syn :
[C-type lectin-like molecule 1; CLL-1; Dendritic cell-associated lectin 2; DCAL-2; Myeloid inhibitory C-type lectin-like receptor; MICL; CLEC12A; CLL1; DCAL2; MICL]
other names :
[C-type lectin domain family 12 member A isoform 3; C-type lectin domain family 12 member A; C-type lectin domain family 12 member A; C-type lectin domain family 12 member A; C-type lectin-like molecule 1; CLL-1; Dendritic cell-associated lectin 2; DCAL-2; Myeloid inhibitory C-type lectin-like receptor; MICL]
products gene name :
[CLEC12A]
other gene names :
[CLEC12A; CLEC12A; CLL1; MICL; CD371; CLL-1; DCAL-2; CLL1; DCAL2; MICL; CLL-1; DCAL-2; MICL]
uniprot entry name :
CL12A_HUMAN
reactivity :
Human, Mouse
purity :
Antigen Affinity Purified
storage stability :
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB:1:500-2000. IHC:1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant human C-type lectin domain family 12 member A protein(66-265aa). Species: Human. Research Area: Signal Transduction
products description :
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
ncbi acc num :
NP_001193939.1
ncbi gb acc num :
NM_001207010.1
ncbi summary :
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]
uniprot summary :
CLEC12A: Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13.2. Cellular Component: integral to membrane; plasma membrane. Molecular Function: carbohydrate binding