product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human Aquaporin-4 polyclonal Antibody(AQP4)
catalog :
MBS1491961
quantity :
0.05 mL
price :
120 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
MyBioSource MBS1491961 image 1
Western blot. All lanes: Aquaporin-4 antibody at 2ug/ml. Lane 1:mouse brain tissue. Lane 2:mouse heart tissue. Lane 3:mouse kidney tissue. Secondary. Goat polyclonal to rabbit at 1/10000 dilution. Predicted band size: 35,33 kDa. Observed band size: 35 kDa.
product information
catalog number :
MBS1491961
products type :
Antibody
products full name :
Rabbit anti-human Aquaporin-4 polyclonal Antibody(AQP4)
products short name :
[Aquaporin-4]
products name syn :
[Aquaporin-4 (AQP-4) (Mercurial-insensitive water channel) (MIWC) (WCH4),AQP4]
other names :
[aquaporin-4 isoform M1; Aquaporin-4; aquaporin-4; aquaporin 4; Mercurial-insensitive water channel; MIWC; WCH4]
products gene name :
[AQP4]
other gene names :
[AQP4; AQP4; MIWC; WCH4; AQP-4; MIWC]
uniprot entry name :
AQP4_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
323
purity :
Antigen Affinity Purified
form :
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Recommended dilution: WB:1:500-2000
image1 heading :
Western Blot (WB)
other info1 :
Conjugate: Non-conjugated. Species: Human. Research Area: Signal Transduction. Target Names: AQP4
other info2 :
Immunogen: Recombinant human Aquaporin-4 protein (244-323aa). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9887 / sc-9888 / sc-20812
products description :
Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
ncbi gi num :
4502181
ncbi acc num :
NP_001641.1
ncbi gb acc num :
NM_001650.5
uniprot acc num :
P55087
ncbi pathways :
Aquaporin-mediated Transport Pathway (1269944); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Passive Transport By Aquaporins Pathway (1269945); SIDS Susceptibility Pathways (198901); Spinal Cord Injury Pathway (739007); Transmembrane Transport Of Small Molecules Pathway (1269903); Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway (1269946); Vasopressin-regulated Water Reabsorption Pathway (143700); Vasopressin-regulated Water Reabsorption Pathway (143631)
ncbi summary :
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]
uniprot summary :
AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described. Protein type: Channel, misc.; Transporter; Membrane protein, multi-pass; Transporter, aquaporin family; Membrane protein, integral. Chromosomal Location of Human Ortholog: 18q11.2-q12.1. Cellular Component: basolateral plasma membrane; cytoplasm; external side of plasma membrane; integral to membrane; plasma membrane. Molecular Function: glycerol channel activity; water channel activity; water transporter activity. Biological Process: glycerol transport; multicellular organismal water homeostasis; renal water homeostasis; transmembrane transport; transport; water transport
size1 :
0.05 mL
price1 :
120 USD
size2 :
0.1 mL
price2 :
160
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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