catalog number :
MBS1491542
products full name :
Rabbit anti-human Clathrin heavy chain 2 polyclonal Antibody, Biotin conjugated
products short name :
[Clathrin heavy chain 2]
products name syn :
[Clathrin heavy chain on chromosome 22; CLH-22; CLTCL1; CLH22; CLTCL; CLTD]
other names :
[clathrin heavy chain 2 isoform 2; Clathrin heavy chain 2; clathrin heavy chain 2; clathrin heavy chain like 1; Clathrin heavy chain on chromosome 22; CLH-22]
other gene names :
[CLTCL1; CLTCL1; CLTD; CHC22; CLH22; CLTCL; CLH22; CLTCL; CLTD; CLH-22]
uniprot entry name :
CLH2_HUMAN
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Biotin
other info2 :
Immunogen: Recombinant Human Clathrin heavy chain 2 protein (1423-1566AA). Research Area: Signal Transduction. Species: Homo sapiens (Human)
products description :
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network
ncbi acc num :
NP_001826.3
ncbi gb acc num :
NM_001835.3
ncbi pathways :
Axon Guidance Pathway (1270303); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); Developmental Biology Pathway (1270302); EPH-Ephrin Signaling Pathway (1270330); EPH-ephrin Mediated Repulsion Of Cells Pathway (1270334); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213307); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276); Endocytosis Pathway (102279); Endocytosis Pathway (102181)
ncbi summary :
This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
uniprot summary :
CLTD: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Belongs to the clathrin heavy chain family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 22q11.21. Cellular Component: clathrin coat of trans-Golgi network vesicle; clathrin-coated vesicle; coated pit; early endosome; late endosome; membrane; plasma membrane; recycling endosome; spindle; trans-Golgi network. Molecular Function: protein binding; signal transducer activity; structural molecule activity. Biological Process: anatomical structure morphogenesis; intracellular protein transport; mitosis; positive regulation of glucose import; receptor-mediated endocytosis; retrograde transport, endosome to Golgi; signal transduction