catalog number :
MBS1490907
products full name :
Rabbit anti-Rabies virus Nucleoprotein polyclonal Antibody, FITC
products short name :
Rabies virus Nucleoprotein
products name syn :
NP; Nucleocapsid protein; Protein N; N
other names :
Nucleoprotein; Nucleoprotein; Nucleocapsid protein; Protein N
other gene names :
N; NP; Protein N
uniprot entry name :
NCAP_RABVA
reactivity :
Rabies virus
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA). Not yet tested in other applications.
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: FITC
other info2 :
Immunogen: Recombinant Rabies virus Nucleoprotein protein
products description :
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.
ncbi mol weight :
50,748 Da