product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human Stress-induced-phosphoprotein 1 polyclonal Antibody, Biotin conjugated
catalog :
MBS1490901
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1490901
products type :
Antibody
products full name :
Rabbit anti-human Stress-induced-phosphoprotein 1 polyclonal Antibody, Biotin conjugated
products short name :
[Stress-induced-phosphoprotein 1]
products name syn :
[Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein)(Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive proteinIEF SSP 3521), STIP1]
other names :
[stress-induced-phosphoprotein 1 isoform a; Stress-induced-phosphoprotein 1; stress-induced-phosphoprotein 1; stress induced phosphoprotein 1; Hsc70/Hsp90-organizing protein; Hop; Renal carcinoma antigen NY-REN-11; Transformation-sensitive protein IEF SSP 3521]
products gene name :
[STIP1]
other gene names :
[STIP1; STIP1; HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521; STI1; Hop]
uniprot entry name :
STIP1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
590
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Biotin. Relevance: Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB). Research Area: Signal Transduction
other info2 :
Immunogen: Recombinant human Stress-induced-phosphoprotein 1 protein (1-543AA). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27962 / sc-27963 / sc-292778
products description :
Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
ncbi gi num :
544063423
ncbi acc num :
NP_001269581.1
ncbi gb acc num :
NM_001282652.1
uniprot acc num :
P31948
ncbi pathways :
Prion Diseases Pathway (101144); Prion Diseases Pathway (100065)
ncbi summary :
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]
uniprot summary :
STI1: a protein that is apparently involved in the response to stress. Specifically interacts with the C-terminal tails of Hsp70 and Hsp90 via TPR1 and TPR2A domains. Deletion of STI1 reduces the activity of the glucocorticoid receptor, a Hsp90 target protein. Phosphorylated in vitro by p90RSK and casein kinase II. Protein type: Chaperone. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: Golgi apparatus; myelin sheath; nucleus; protein complex. Molecular Function: chaperone binding; Hsp70 protein binding; protein binding; protein C-terminus binding. Biological Process: response to stress
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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