catalog number :
MBS1490862
products full name :
Rabbit anti-mouse Fibroblast growth factor 1 polyclonal Antibody
products short name :
[Fibroblast growth factor 1]
products name syn :
[Fibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Heparin-binding growth factor 1) (HBGF-1), Fgf1, Fgf-1 Fgfa]
other names :
[fibroblast growth factor 1; Fibroblast growth factor 1; fibroblast growth factor 1; fibroblast growth factor 1; Acidic fibroblast growth factor; aFGF; Heparin-binding growth factor 1; HBGF-1]
other gene names :
[Fgf1; Fgf1; Fam; Fgfa; Dffrx; Fgf-1; Fgf-1; Fgfa; FGF-1; aFGF; HBGF-1]
uniprot entry name :
FGF1_MOUSE
reactivity :
Mouse, Human
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended Dilution: WB: 1:500-1:5000, IHC: 1:10-1:100
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant Mouse Fibroblast growth factor 1 protein (16-155AA). Conjugate: Non-conjugated. Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Species: Mouse. Research Area: Cardiovascular
products description :
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
ncbi acc num :
NP_034327.1
ncbi gb acc num :
NM_010197.3
ncbi pathways :
ARMS-mediated Activation Pathway (1324638); Adaptive Immune System Pathway (1323640); Axon Guidance Pathway (1323598); Cytokine Signaling In Immune System Pathway (1323763); DAP12 Interactions Pathway (1323743); DAP12 Signaling Pathway (1323744); Developmental Biology Pathway (1323597); Downstream Signal Transduction Pathway (1324645); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (1323654); Downstream Signaling Of Activated FGFR1 Pathway (1324563)
uniprot summary :
FGF1: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP1. Part of a Cu(2+)-dependent multiprotein aggregate containing FGF1, S100A13 and SYT1. Interacts with SYT1. Interacts with S100A13. Belongs to the heparin-binding growth factors family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine; Cell development/differentiation; Motility/polarity/chemotaxis. Cellular Component: cytoplasm; cytosol; extracellular region; extracellular space; nucleolus; nucleoplasm; nucleus; proteinaceous extracellular matrix. Molecular Function: fibroblast growth factor receptor binding; growth factor activity; heparin binding; Hsp70 protein binding; protein binding; receptor binding. Biological Process: angiogenesis; cardiac muscle cell proliferation; cell differentiation; cell proliferation; fibroblast growth factor receptor signaling pathway; induction of an organ; lung development; multicellular organismal development; positive regulation of angiogenesis; positive regulation of cell division; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of cholesterol biosynthetic process; positive regulation of epithelial cell proliferation; positive regulation of MAP kinase activity; positive regulation of protein amino acid phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent