catalog number :
MBS1490646
products full name :
Rabbit anti-human N-acetylmuramoyl-L-alanine amidase polyclonal Antibody
products short name :
[N-acetylmuramoyl-L-alanine amidase]
products name syn :
[N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) (Peptidoglycan recognition protein 2) (Peptidoglycan recognition protein long) (PGRP-L), PGLYRP2, PGLYRPL PGRPL]
other names :
[N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase; peptidoglycan recognition protein 2; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L]
other gene names :
[PGLYRP2; PGLYRP2; tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha; PGLYRPL; PGRPL; PGRP-L]
uniprot entry name :
PGRP2_HUMAN
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:20-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Species: Human. Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54941 / sc-54662 / sc-54943 / sc-50470. Research Area: Immunology
products description :
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
ncbi acc num :
NP_443122.3
ncbi gb acc num :
NM_052890.3
ncbi mol weight :
68,000 Da
ncbi summary :
This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]
uniprot summary :
PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Receptor, misc.; Hydrolase; EC 3.5.1.28. Chromosomal Location of Human Ortholog: 19p13.12. Cellular Component: intracellular; membrane. Molecular Function: N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity; zinc ion binding. Biological Process: defense response to Gram-positive bacterium; detection of bacterium; innate immune response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation during immune response; pattern recognition receptor signaling pathway; peptide amidation; peptidoglycan catabolic process; regulation of inflammatory response