catalog number :
MBS1490517
products full name :
Rabbit anti-Rabies virus Nucleoprotein polyclonal Antibody
products short name :
[Rabies virus Nucleoprotein]
products name syn :
[NP; Nucleocapsid protein; Protein N; N]
other names :
[Nucleoprotein; Nucleoprotein; Nucleocapsid protein; Protein N]
other gene names :
[N; NP; Protein N]
uniprot entry name :
NCAP_RABVA
reactivity :
Rabies virus
purity :
>95%, Protein G purified
form :
Liquid. Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze
tested application :
ELISA (EIA)
image1 heading :
SDS-PAGE
other info1 :
Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant Rabies virus Nucleoprotein protein (1-450AA)
products description :
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
ncbi mol weight :
50,748 Da
uniprot summary :
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases ().