catalog number :
MBS1490193
products full name :
Rabbit anti-human Antigen KI-67 polyclonal Antibody, HRP conjugated
products short name :
Antigen KI-67
other names :
antigen KI-67 isoform 2; Antigen KI-67; antigen KI-67; marker of proliferation Ki-67
products gene name :
MKI67
other gene names :
MKI67; MKI67; KIA; MIB-; MIB-1; PPP1R105
uniprot entry name :
KI67_HUMAN
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP
other info2 :
Immunogen: Recombinant human Antigen KI-67 protein
products description :
Thought to be required for maintaining cell proliferation.
ncbi acc num :
NP_001139438.1
ncbi gb acc num :
NM_001145966.1
ncbi mol weight :
319,444 Da
ncbi summary :
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
uniprot summary :
KI-67: a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers. Protein type: Cell cycle regulation; Nucleolus. Chromosomal Location of Human Ortholog: 10q26.2. Cellular Component: chromosome, pericentric region; condensed chromosome; cytoplasm; membrane; nucleolus; nucleus. Molecular Function: ATP binding; protein binding; protein C-terminus binding. Biological Process: cell proliferation; DNA metabolic process; hyaluronan metabolic process; meiosis; organ regeneration; response to organic cyclic substance