product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-Influenza A virus Nucleoprotein polyclonal Antibody
catalog :
MBS1490101
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1490101
products type :
Antibody
products full name :
Rabbit anti-Influenza A virus Nucleoprotein polyclonal Antibody
products short name :
Influenza A virus Nucleoprotein
products name syn :
Nucleocapsid protein; Protein N
other names :
nucleocapsid protein; Nucleoprotein; nucleocapsid protein; Nucleocapsid protein; Protein N
products gene name :
NP
other gene names :
NP; NP; Protein N
uniprot entry name :
NCAP_I34A1
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Influenza A virus
sequence length :
498
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA). Not yet tested in other applications.
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant Influenza A virus Nucleoprotein protein
products description :
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
ncbi gi num :
8486130
ncbi acc num :
NP_040982.1
ncbi gb acc num :
NC_002019.1
uniprot acc num :
P03466
ncbi mol weight :
56,210 Da
ncbi pathways :
Assembly Of Viral Components At The Budding Site Pathway (1269125); Budding Pathway (1269128); Disease Pathway (1268854); Entry Of Influenza Virion Into Host Cell Via Endocytosis Pathway (1269110); Export Of Viral Ribonucleoproteins From Nucleus Pathway (1269121); Fusion And Uncoating Of The Influenza Virion Pathway (1269111); Fusion Of The Influenza Virion To The Host Cell Endosome Pathway (1269112); Infectious Disease Pathway (1269056); Influenza A Virus Infection Pathway (920973); Influenza Infection Pathway (1269108)
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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