catalog number :
MBS1489827
products full name :
Rabbit anti-Escherichia coli Glutamate decarboxylase alpha polyclonal Antibody
products short name :
Glutamate decarboxylase alpha
products name syn :
gadS; b3517; JW3485
other names :
glutamate decarboxylase A, PLP-dependent; Glutamate decarboxylase alpha; glutamate decarboxylase A, PLP-dependent
products gene name :
gadA
other gene names :
gadA; gadA; ECK3502; gadS; JW3485; gadS; GAD-alpha
uniprot entry name :
DCEA_ECOLI
reactivity :
Escherichia coli
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA). Not yet tested in other applications.
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant Escherichia coli Glutamate decarboxylase alpha protein
products description :
Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.
ncbi acc num :
NP_417974.1
ncbi gb acc num :
NC_000913.3
ncbi mol weight :
52,685 Da
ncbi pathways :
Alanine, Aspartate And Glutamate Metabolism Pathway (100068); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Biosynthesis Of Secondary Metabolites Pathway (148665); Butanoate Metabolism Pathway (1083); Butanoate Metabolism Pathway (391); GABA (gamma-Aminobutyrate) Shunt Pathway (405185); GABA (gamma-Aminobutyrate) Shunt Pathway (468220); L-glutamate Degradation IX (via 4-aminobutanoate) Pathway (233); L-glutamate Degradation IX (via 4-aminobutanoate) Pathway (139667); Metabolic Pathways (131985)
ncbi summary :
RpoS regulon. [More information is available at EcoGene: EG50009]. GadA, a glutamate decarboxylase enzyme, is part of the glutamate-dependent acid resistance system 2 (AR2) which confers resistance to extreme acid conditions. [More information is available at EcoCyc: EG50009].