catalog number :
MBS1489822
products full name :
Rabbit antiL-mouse Leukocyte immunoglobulin-like receptor subfamily B member 3 polyclonal Antibody
products short name :
Rabbit antiL-Leukocyte immunoglobulin-like receptor subfamily B member 3
products name syn :
LIR-3; Leukocyte immunoglobulin-like receptor 3; Cell-surface glycoprotein p91; Paired immunoglobulin-like receptor B; PIR-B; Lilrb3; Pirb
other names :
leukocyte immunoglobulin-like receptor subfamily B member 3; Leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor subfamily B member 3; paired Ig-like receptor B; Cell-surface glycoprotein p91; Paired immunoglobulin-like receptor B; PIR-B
other gene names :
Pirb; Lilrb3; Gp91; LIR-3; PIR-B; Lilrb3; Pirb; LIR-3; Leukocyte immunoglobulin-like receptor 3; PIR-B
uniprot entry name :
LIRB3_MOUSE
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA). Not yet tested in other applications.
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant mouse eukocyte immunoglobulin-like receptor subfamily B member 3 protein
products description :
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
ncbi acc num :
NP_035225.2
ncbi gb acc num :
NM_011095.2
ncbi mol weight :
93,054 Da
ncbi pathways :
B Cell Receptor Signaling Pathway (83278); B Cell Receptor Signaling Pathway (492); Osteoclast Differentiation Pathway (193149); Osteoclast Differentiation Pathway (193096); Spinal Cord Injury Pathway (739004)
uniprot summary :
Pirb: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B- cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). Protein type: Membrane protein, integral. Cellular Component: integral to membrane; membrane; plasma membrane. Biological Process: adaptive immune response; B cell homeostasis; B cell mediated immunity; cytokine and chemokine mediated signaling pathway; immune system process; myeloid dendritic cell differentiation