product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-Human Prostate-specific antigen polyclonal Antibody, HRP conjugated
catalog :
MBS1489254
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1489254
products type :
Antibody
products full name :
Rabbit anti-Human Prostate-specific antigen polyclonal Antibody, HRP conjugated
products short name :
[Prostate-specific antigen]
products name syn :
[Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase), KLK3, APS]
other names :
[prostate-specific antigen isoform 3 preproprotein; Prostate-specific antigen; prostate-specific antigen; kallikrein related peptidase 3; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase]
other gene names :
[KLK3; KLK3; APS; PSA; hK3; KLK2A1; APS; PSA; Seminin]
uniprot entry name :
KLK3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Upon receipt, aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP
other info2 :
Immunogen: Recombinant Human Prostate-specific antigen protein (28-261AA). Species: Homo sapiens (Human). Research Area: Neuroscience. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7638
products description :
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
ncbi gi num :
71834853
ncbi acc num :
NP_001025218.1
ncbi gb acc num :
NM_001030047.1
uniprot acc num :
P07288
ncbi pathways :
Activated PKN1 Stimulates Transcription Of AR (androgen Receptor) Regulated Genes KLK2 And KLK3 Pathway (1269513); Androgen Receptor Signaling Pathway (198806); Coregulation Of Androgen Receptor Activity Pathway (138085); FOXA1 Transcription Factor Network Pathway (137979); Metabolism Of Proteins Pathway (1268677); Pathways In Cancer (83105); Prostate Cancer Pathway (755440); Prostate Cancer Pathway (83111); Prostate Cancer Pathway (523); RHO GTPase Effectors Pathway (1269509)
ncbi summary :
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
PSA: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. Forms heterodimer with SERPINA5. Inhibited by SERPINA5. Activity is strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. Belongs to the peptidase S1 family. Kallikrein subfamily. Protein type: EC 3.4.21.77; Secreted, signal peptide; Protease; Secreted. Chromosomal Location of Human Ortholog: 19q13.41. Cellular Component: extracellular region; extracellular space; nucleus; protein complex. Molecular Function: endopeptidase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; protein binding; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: antibacterial peptide production; cellular protein metabolic process; negative regulation of angiogenesis; proteolysis; small GTPase mediated signal transduction
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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