Rabbit anti-human Erythropoietin polyclonal Antibody, HRP conjugated | MyBioSource MBS1489013 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti-human Erythropoietin polyclonal Antibody, HRP conjugated

catalog :

MBS1489013

quantity :

0.05 mg

price :

160 USD

clonality :

polyclonal

host :

rabbit

conjugate :

HRP

reactivity :

human

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS1489013

products type :

Antibody

products full name :

Rabbit anti-human Erythropoietin polyclonal Antibody, HRP conjugated

products short name :

Erythropoietin

products name syn :

INN=Epoetin

other names :

erythropoietin; Erythropoietin; erythropoietin; erythropoietin; INN: Epoetin

products gene name :

EPO

other gene names :

EPO; EPO; EP; MVCD2

uniprot entry name :

EPO_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

193

purity :

Caprylic Acid Ammonium Sulfate Precipitation Purified

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

tested application :

Western Blot (WB), ELISA (EIA). Not yet tested in other applications.

other info1 :

Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP

other info2 :

Immunogen: Recombinant human Erythropoietin protein

products description :

Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.

ncbi gi num :

62240997

ncbi acc num :

NP_000790.2

ncbi gb acc num :

NM_000799.2

uniprot acc num :

P01588

ncbi mol weight :

21,307 Da

ncbi pathways :

Cellular Response To Hypoxia Pathway (1270415); Cellular Responses To Stress Pathway (1270414); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); EPO Receptor Signaling Pathway (198882); EPO Signaling Pathway (138051); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045); HIF-2-alpha Transcription Factor Network Pathway (137956); Hematopoietic Cell Lineage Pathway (83078)

ncbi summary :

This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq, Jul 2008]

uniprot summary :

EPO: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Genetic variation in EPO is associated with susceptbility to microvascular complications of diabetes type 2 (MVCD2). These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Belongs to the EPO/TPO family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7q22. Cellular Component: cell surface; extracellular region; extracellular space. Molecular Function: erythropoietin receptor binding; hormone activity; protein binding; protein kinase activator activity. Biological Process: activation of protein kinase activity; acute-phase response; aging; apoptosis; blood circulation; embryo implantation; erythrocyte differentiation; erythrocyte maturation; hemoglobin biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; peptidyl-serine phosphorylation; positive regulation of activated T cell proliferation; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of Ras protein signal transduction; positive regulation of transcription, DNA-dependent; positive regulation of tyrosine phosphorylation of Stat5 protein; response to axon injury; response to electrical stimulus; response to estrogen stimulus; response to hyperoxia; response to lipopolysaccharide; response to salt stress; response to testosterone stimulus; response to vitamin A; signal transduction. Disease: Microvascular Complications Of Diabetes, Susceptibility To, 2

size1 :

0.05 mg

price1 :

160 USD

size2 :

0.1 mg

price2 :

235

more info or order :

MyBioSource product webpage