catalog number :
MBS1488994
products full name :
Rabbit anti-human Tetraspanin-7 polyclonal Antibody
products short name :
[Tetraspanin-7]
products name syn :
[Cell surface glycoprotein A15 Membrane component chromosome X surface marker 1 T-cell acute lymphoblastic leukemia-associated antigen 1 Transmembrane 4 superfamily member 2 CD_antigen=CD231 TSPAN7 A15; DXS1692E; MXS1; TM4SF2]
other names :
[tetraspanin-7; Tetraspanin-7; tetraspanin-7; tetraspanin 7; Cell surface glycoprotein A15; Membrane component chromosome X surface marker 1; T-cell acute lymphoblastic leukemia-associated antigen 1; TALLA-1; Transmembrane 4 superfamily member 2; CD_antigen: CD231]
other gene names :
[TSPAN7; TSPAN7; A15; MXS1; CD231; MRX58; CCG-B7; TM4SF2; TALLA-1; TM4SF2b; DXS1692E; A15; DXS1692E; MXS1; TM4SF2; Tspan-7; TALLA-1]
uniprot entry name :
TSN7_HUMAN
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Recommended dilution: . IHC: 1:20-1:200. IF: 1:50-1:200
image1 heading :
Immunofluorescence (IF)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated. Relevance: May be involved in cell proliferation and cell motility. Research Area: Signal Transduction
other info2 :
Immunogen: Recombinant Human Tetraspanin-7 protein (113-223AA)
. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-139572 / sc-139573
products description :
May be involved in cell proliferation and cell motility.
ncbi acc num :
NP_004606.2
ncbi gb acc num :
NM_004615.3
ncbi pathways :
Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)
ncbi summary :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
uniprot summary :
TSPAN7: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Defects in TSPAN7 are the cause of mental retardation X- linked type 58 (MRX58). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: Xp11.4. Cellular Component: integral to plasma membrane. Biological Process: cell surface receptor linked signal transduction; viral reproduction. Disease: Mental Retardation, X-linked 58