catalog number :
MBS1488951
products full name :
Rabbit anti-Human Transmembrane emp24 domain-containing protein 9 polyclonal Antibody
products short name :
[Transmembrane emp24 domain-containing protein 9]
products name syn :
[Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25), TMED9, GP25L2]
other names :
[transmembrane emp24 domain-containing protein 9; Transmembrane emp24 domain-containing protein 9; transmembrane emp24 domain-containing protein 9; transmembrane p24 trafficking protein 9; GMP25; Glycoprotein 25L2; p24 family protein alpha-2; p24alpha2; p25]
other gene names :
[TMED9; TMED9; p25; GMP25; HSGP25L2G; GP25L2; p24alpha2]
uniprot entry name :
TMED9_HUMAN
reactivity :
Human, Mouse
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA, Western Blot (WB)
app notes :
Recommended dilution: WB: 1:1000-1:5000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant Human Transmembrane emp24 domain-containing protein 9 protein (40-197AA). Conjugate: Non-conjugated. Storage Buffer: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2. Species: Human. Research Area: Signal Transduction
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-248851
products description :
Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.
ncbi acc num :
NP_059980.2
ncbi gb acc num :
NM_017510.4
ncbi pathways :
Asparagine N-linked Glycosylation Pathway (1268714); COPI-mediated Anterograde Transport Pathway (1339109); ER To Golgi Anterograde Transport Pathway (1268726); Membrane Trafficking Pathway (1269877); Metabolism Of Proteins Pathway (1268677); Post-translational Protein Modification Pathway (1268701); Transport To The Golgi And Subsequent Modification Pathway (1268725); Vesicle-mediated Transport Pathway (1269876)
uniprot summary :
TMED9: Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer- dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB. Belongs to the EMP24/GP25L family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 5q35.3. Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; ER-Golgi intermediate compartment; ER-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; integral to membrane; trans-Golgi network transport vesicle; transport vesicle. Molecular Function: protein binding; syntaxin binding. Biological Process: cellular protein metabolic process; COPI coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; Golgi organization and biogenesis; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; protein exit from endoplasmic reticulum