catalog number :
MBS1488577
products full name :
Rabbit anti-human C-reactive protein polyclonal Antibody, HRP conjugated
products short name :
[C-reactive protein]
products name syn :
[C-reactive protein [Cleaved into: C-reactive protein(1-205)], CRP, PTX1]
other names :
[C-reactive protein; C-reactive protein; C-reactive protein; C-reactive protein, pentraxin-related]
products gene name :
[CRP]
other gene names :
[CRP; CRP; PTX1; PTX1]
uniprot entry name :
CRP_HUMAN
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze
tested application :
ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP. Relevance: CRP2 is a novel substrate of cGKI in neurons and smooth muscle of the small intestine. Species: Homo sapiens (Human). Research Area: Immunology
other info2 :
Immunogen: Recombinant Human C-reactive protein (19-224AA). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18304 / sc-18306 / sc-30047
products description :
CRP2 is a novel substrate of cGKI in neurons and smooth muscle of the small intestine.
ncbi acc num :
NP_000558.2
ncbi gb acc num :
NM_000567.2
ncbi pathways :
Classical Antibody-mediated Complement Activation Pathway (1269246); Complement Cascade Pathway (1269241); Creation Of C4 And C2 Activators Pathway (1269243); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (1269170); Initial Triggering Of Complement Pathway (1269242); Innate Immune System Pathway (1269203); Selenium Pathway (198825)
ncbi summary :
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
uniprot summary :
CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q23.2. Cellular Component: extracellular region; extracellular space. Molecular Function: calcium ion binding; choline binding; complement component C1q binding; low-density lipoprotein binding; low-density lipoprotein receptor binding; protein binding; virion binding. Biological Process: acute-phase response; defense response to Gram-positive bacterium; inflammatory response; negative regulation of vasodilation; opsonization; positive regulation of superoxide release