catalog number :
MBS1488479
products full name :
Rabbit anti-human Aspartate aminotransferase, cytoplasmic polyclonal Antibody
products short name :
Aspartate aminotransferase
products name syn :
Glutamate oxaloacetate transaminase 1; Transaminase; GOT1
other names :
aspartate aminotransferase, cytoplasmic; Aspartate aminotransferase, cytoplasmic; aspartate aminotransferase, cytoplasmic; glutamic-oxaloacetic transaminase 1, soluble; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A
other gene names :
GOT1; GOT1; AST1; cCAT; GIG18; cAspAT; ASTQTL1; cAspAT; cCAT
uniprot entry name :
AATC_HUMAN
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Non-conjugated
other info2 :
Immunogen: Recombinant human Aspartate aminotransferase, cytoplasmic protein
products description :
Plays a key role in amino acid metabolism.
ncbi acc num :
NP_002070.1
ncbi gb acc num :
NM_002079.2
ncbi mol weight :
44,147 Da
ncbi pathways :
2-Oxocarboxylic Acid Metabolism Pathway (714485); 2-Oxocarboxylic Acid Metabolism Pathway (717400); Alanine And Aspartate Metabolism Pathway (198783); Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Amino Acid Synthesis And Interconversion (transamination) Pathway (1270159); Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Arginine Biosynthesis Pathway (82943); Arginine Biosynthesis Pathway (306)
ncbi summary :
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [provided by RefSeq, Jul 2008]
uniprot summary :
GOT1: Plays a key role in amino acid metabolism. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Protein type: Transferase; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; EC 2.6.1.3; EC 2.6.1.1; Amino Acid Metabolism - alanine, aspartate and glutamate. Chromosomal Location of Human Ortholog: 10q24.1-q25.1. Cellular Component: cytoplasm; cytosol; lysosome; mitochondrion; nerve terminal; nucleus. Molecular Function: aspartate transaminase activity; carboxylic acid binding; cysteine transaminase activity; identical protein binding; phosphatidylserine decarboxylase activity; pyridoxal phosphate binding. Biological Process: 2-oxoglutarate metabolic process; amino acid biosynthetic process; aspartate biosynthetic process; aspartate catabolic process; aspartate metabolic process; carbohydrate metabolic process; cellular response to insulin stimulus; fatty acid homeostasis; gluconeogenesis; glucose metabolic process; glutamate catabolic process to 2-oxoglutarate; glutamate catabolic process to aspartate; glutamate metabolic process; glycerol biosynthetic process; methionine salvage; Notch signaling pathway; oxaloacetate metabolic process; polyamine metabolic process; response to glucocorticoid stimulus; sulfur amino acid metabolic process. Disease: Aspartate Aminotransferase, Serum Level Of, Quantitative Trait Locus 1