product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse anti-Human Osteopontin monoclonal Antibody
catalog :
MBS1488153
quantity :
0.05 mg
price :
185 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS1488153 image 1
Immunohistochemical of paraffin-embedded human colon cancer using MBS1488153 at dilution of 1:200
image 2 :
MyBioSource MBS1488153 image 2
Immunohistochemical of paraffin-embedded human Kidney tissue using MBS1488153 at dilution of 1:200
image 3 :
MyBioSource MBS1488153 image 3
All Lanes Mouse anti human OPN monoclonal antibody at at 2ug/ml. Lane 1:mouse kidney tissue lysate. Secondary Goat polyclonal to Mouse IgG at 1/5000 dilution. Predicted band size: 34.5 kDa. Observed band size: 33,36,34kDa. Additional bands at: 50 kDa.
product information
catalog number :
MBS1488153
products type :
Antibody
products full name :
Mouse anti-Human Osteopontin monoclonal Antibody
products short name :
[Osteopontin]
products name syn :
[Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin; BNSP; PSEC0156]
other names :
[osteopontin isoform OPN-b; Osteopontin; osteopontin; secreted phosphoprotein 1; Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin]
products gene name :
[OPN]
other gene names :
[SPP1; SPP1; OPN; BNSP; BSPI; ETA-1; BNSP; OPN; SPP-1]
uniprot entry name :
OSTP_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
host :
Mouse
reactivity :
Human
sequence length :
300
specificity :
Specific for human Osteopontin denatured and native forms
purity :
>95%, Protein G Purified
form :
Liquid
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:5000. IHC: 1:50-1:500
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Western Blot (WB)
other info2 :
Product Type: Monoclonal Antibody. Conjugate: Non-conjugated. Immunogen: Recombinant Human Osteopontin. Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21742 / sc-73631
products description :
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity
ncbi gi num :
4759166
ncbi acc num :
NP_000573.1
ncbi gb acc num :
NM_000582.2
uniprot acc num :
1B2C2
ncbi summary :
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
uniprot summary :
osteopontin: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Belongs to the osteopontin family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q22.1. Cellular Component: apical part of cell; cell projection; extracellular region; extracellular space; perinuclear region of cytoplasm. Molecular Function: cytokine activity; extracellular matrix binding; protein binding. Biological Process: biomineral formation; cell adhesion; decidualization; embryo implantation; extracellular matrix disassembly; extracellular matrix organization and biogenesis; inflammatory response; negative regulation of collateral sprouting of intact axon in response to injury; neutrophil chemotaxis; osteoblast differentiation; positive regulation of bone resorption; response to steroid hormone stimulus; response to vitamin D
size1 :
0.05 mg
price1 :
185 USD
size2 :
0.1 mg
price2 :
265
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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