product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Semaphorin-3A
catalog :
MBS1481563
quantity :
0.01 mg (E-Coli)
price :
110 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1481563
products type :
Recombinant Protein
products full name :
Recombinant Rat Semaphorin-3A
products short name :
Semaphorin-3A
products name syn :
Semaphorin III; Sema III
other names :
semaphorin-3A; Semaphorin-3A; semaphorin-3A; semaphorin 3A; Semaphorin III; Sema III
products gene name :
Sema3a
other gene names :
Sema3a; Sema3a; Sema III
uniprot entry name :
SEM3A_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
22-772
sequence length :
772
sequence :
NYANGKNNVPRLKLSYKEMLESNNVITFNGLANSSSYHT
FLLDEERSRLYVGAKDHIFSFNLVNIKDFQKIVWPVSYT
RRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAF
HPICTYIEVGHHPEDNIFKLQDSHFENGRGKSPYDPKLL
TASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQ
HDSRWLNDPRFISAHLIPESDNPEDDKVYFFFRENAIDG
EHSGKATHARIGQICKNDFGGHRSLVNKWTTFLKARLIC
SVPGPNGIDTHFDELQDVFLMNSKDPKNPIVYGVFTTSS
NIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQG
RVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARSHPAMY
NPVFPINNRPIMIKTDVNYQFTQIVVDRVDAEDGQYDVM
FIGTDVGTVLKVVSVPKETWHDLEEVLLEEMTVFREPTT
ISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAEC
CLARDPYCAWDGSSCSRYFPTAKRRTRRQDIRNGDPLTH
CSDLQHHDNHHGHSLEERIIYGVENSSTFLECSPKSQRA
LVYWQFQRRNEDRKEEIRVGDHIIRTEQGLLLRSLQKKD
SGNYLCHAVEHGFMQTLLKVTLEVIDTEHLEELLHKDDD
GDGSKTKEMSSSMTPSQKVWYRDFMQLINHPNLNTMDEF
CEQVWKRDRKQRRQRPGHSQGSSNKWKHMQESKKGRNRR
THEFERAPRSV
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Rat
products categories :
Cardiovascular
products description :
May be involved in guiding growing axons towards their targets by forming a molecular boundary that instructs axons to engage in the formation of specific nerve tracts. Binds to neuropilin. Involved in the development of the olfactory system and in neuronal control of puberty
products references :
Anatomy of rat semaphorin III/collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis." Giger R.J., Wolfer D.P., De Wit G.M.J., Verhaagen J. J. Comp. Neurol. 375:378-392(1996)
ncbi gi num :
8394255
ncbi acc num :
NP_059006.1
ncbi gb acc num :
NM_017310.1
uniprot acc num :
Q63548
ncbi mol weight :
88,808 Da
ncbi pathways :
Axon Guidance Pathway (83457); Axon Guidance Pathway (476); Axon Guidance Pathway (1333217); CRMPs In Sema3A Signaling Pathway (1333224); Developmental Biology Pathway (1333216); SEMA3A-Plexin Repulsion Signaling By Inhibiting Integrin Adhesion Pathway (1333222); Sema3A PAK Dependent Axon Repulsion Pathway (1333223); Semaphorin Interactions Pathway (1333218)
ncbi summary :
induces neuronal cell death; induces apoptosis of retinal ganglion cells in response to injury [RGD, Feb 2006]
uniprot summary :
SEMA3A: May be involved in guiding growing axons towards their targets by forming a molecular boundary that instructs axons to engage in the formation of specific nerve tracts. Binds to neuropilin. Involved in the development of the olfactory system and in neuronal control of puberty (By similarity). Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis. Cellular Component: axon; dendrite; extracellular space. Molecular Function: chemorepellent activity; semaphorin receptor binding. Biological Process: apoptosis; axon extension involved in axon guidance; axon guidance; axonal fasciculation; branchiomotor neuron axon guidance; dendrite morphogenesis; facial nerve structural organization; gonadotrophin-releasing hormone neuronal migration to the hypothalamus; motor axon guidance; negative chemotaxis; negative regulation of axon extension; negative regulation of axon extension involved in axon guidance; nerve development; neural crest cell migration; neuron migration; olfactory bulb development; regulation of axon extension involved in axon guidance; regulation of heart rate; trigeminal nerve structural organization
size1 :
0.01 mg (E-Coli)
price1 :
110 USD
size2 :
0.05 mg (E-Coli)
price2 :
190
size3 :
0.2 mg (E-Coli)
price3 :
460
size4 :
0.5 mg (E-Coli)
price4 :
750
size5 :
1 mg (E-Coli)
price5 :
1180
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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